Cell signaling

Understanding cell signaling is essential for improving our ability to regenerate tissues and repair damaged organs. Cell signaling refers to the complex network of communication that occurs within and between cells, and it plays a crucial role in determining how cells respond to their environment and each other. We work on advanced computational models to unravel the dynamics of cell signaling crosstalk and gain a better understanding of how it affects tissue regeneration. 

Publications

Karagöz, Z., Passanha, F., Robeerst, L., van Griensven, M., LaPointe, V., Carlier, A. (2022) Computational evidence for multi-layer crosstalk between cadherin-11 and PDGF pathways. BioRxiv

Paes, D., Hermans, S., van den Hove, D., Vanmierlo, T., Prickaerts, J., Carlier, A. (2022) Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types. Biophysical Journal, https://doi.org/10.1016/j.bpj.2022.06.019