Aurélie Carlier is associate professor at the MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University. She received her PhD degree (2014) in Biomedical Engineering at the KU Leuven, Belgium. Her research interests encompass the computational modelling of biological processes, with a particular focus on bone tissue engineering and cell-biomaterial interactions, using a range of data-driven to mechanistic modelling approaches. Her research achievements have been awarded with a number of distinctions, including three doctoral thesis awards (ESMTB, 2015; ESB, 2015; KUL, 2016). She was also New Scientist Wetenschapstalent 2021 finalist and received a prestigious VENI career development grant (0.25 M€) from the Dutch Science Foundation. She is board member of the Dutch Society for Biomaterials and Tissue Engineering as well as of the European Society of Biomechanics where she serves as chair of the student and education committee. Besides her research, Aurélie is co-founder and chair of FEM (Female Empowerment Maastricht University), a network to discuss and tackle gender issues.
leyla.noroozbabaee@maastrichtuniversity.nl
Leyla is a Research Fellow specializing in computational biophysics, with a focus on developing innovative models to advance our understanding of kidney function. In more detail, she will perform research in computational modeling methods applied to regenerative medicine and more specifically, to kidney toxin transport in microfluidic set-ups, organoid culture systems, and/or bioartificial kidney devices., at the MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University. She received her Ph.D. degree (2016) in computational biophysics at the University of Waikato, New Zealand, where was analyzing the effect of anesthetic drugs on brain activity. In her recent position as a Post-Doctoral Research Fellow at the University of Auckland (2019-2023), Leyla spearheaded the development of a kidney model, that aims to integrate detailed insights from existing research while ensuring modularity and reproducibility. Leyla's research endeavors delve into the intricate mechanisms underlying conditions such as hypertension and diabetes, leveraging integrative mathematical models to provide a comprehensive tool for investigation.
matilde.marradi@maastrichtuniversity.nl
Matilde is from Italy and she studied Biomedical Engineering at Politecnico di Milano. Her Master’s degree focused on Biomechanics and Biomaterials. The course of study was centered in deeply understanding of mechanics
of both hard and soft biological tissues, including fluid dynamics. The second year was mainly dedicated to computational modelling of biological processes. Matilde graduated with a thesis entitled "A patient-specific agent-based modeling framework of restenosis after balloon angioplasty in a superficial femoral artery - effects of mechanical damage and hemodynamics on cellular dynamics". In August 2023, she joined MERLN for her PhD work, within the framework of the Material Driven Regeneration (MDR) consortium. The aim of her project is to develop in silico multiscale models to simulate cell-ECM interactions and fibrotic tissue remodeling.
iga.skorupska@maastrichtuniversity.nl
Iga, originally from Poland, completed her Bachelor's degree in Data Science and Artificial Intelligence. Fascinated by intricate biological systems, she decided to continue her educational journey with a Master's in Systems Biology. Iga is now starting her Ph.D., focusing on Computational Modeling of cAMP Signaling in the context of Alzheimer's disease. Therefore, her research interest lies in uncovering the complexities of the brain on cell level and its connection to this challenging condition. Her PhD is a disciplinary project between MHeNs/ BIOMED (experimental work) and MERLN (computational work).
yagmur.dogay@maastrichtuniversity.nl
Yağmur is from Cyprus and she studied Biomedical Science at The University of Hull. She completed her master's degree in Data Science for Life Sciences at Hanze University of Applied Sciences. After completing her master's, she joined Trinity College Dublin/ ADAPT Centre, where she first worked on the HELICAL project and later contributed to the PARADISE project. Both projects focused on ANCA vasculitis. In April 2025, she joined MERLN for her PhD work and the focus of her work is Automated Knowledge Graphs for Kidney Physiology and Pathology.
Post-doctoral Researchers
Sangita Swapnasrita (2024) Sorbent-Assisted Continuous Flow Peritoneal Dialysis in silico
Hamidreza Jafarinia(2025) Modeling the cell-ECM interface using different computational techniques
Zeynep Karagöz (2024) Dynamic computational models of cell-extracellular matrix and cell-cell interactions
Jasia King (2022) Understanding toxin transport in the proximal tubule: coupling in vitro experiments with computational simulations
Kerbai Said Eroume (2021) In silico modelling of cell shape induced behavior - In silico modeling of cell shape induced behavior.
Henrike Schulze (2023) Computational modeling of macrophage-fibroblast crosstalk.
River Hummel (2023) Image analysis of stretch-activated neuronal growth.
Honasoge K. (2022) Computational modeling of the force-dependent focal adhesion assembly and disassembly
Vanmeulebrouk C. (2022) Computational modeling of cAMP signalingng Computational modeling of cAMP signaling
Al-Baz A. (2022) Computational modeling of sodium handling in proximal tubule during menstrual cycles
Robeerst L. (2021) Computational model of cadherin-RTK crosstalk
Wagner A. (2021) Computational modeling of integrin adhesome dynamics
Vandelaer L. (2020) Stability analysis of cell polarization models
Gonzalez Ovalle A. (2020) Virtual Cell computational modelling of cAMP and phosphodiesterase signalling
Gomes Carvalho de Abreu M. (2020) Modeling TGF-β signaling
Hermans S. (2020) Computational modeling of cAMP signaling
Callens B. (2020) Computational modeling of cadherin signaling
Marques R. (2020) On the influence of hormonal levels on fallopian tube function: a computational study
Bengtsson del Barrio L. (2019) Regulation of mesenchymal stem cell nuclear architecture by micro-topographies
Nikody M. (2019) Optimisation of a proximal-tubule-function-on-chip device: unravelling toxin removal in the nephron
Shen F. (2018) In silico modeling of the YAP-TAZ signaling pathway
Wijnen I. (2017) Investigating mechanotransduction pathways involved in topography-induced cell behavior – the effect of cell culture conditions on EGR-1 and FOS expression
Van Steen B. (2017) Touch and go – topography induced changes in speed and direction of cell migration
Ricca V. (2015) In silico modeling of BMP driven bone formation
Homayounfar A. (2015) Mathematical modeling of blood flow
Jacobs M. (2014) Mathematical modeling of angiogenesis during tumor growth
Wiktoria Muzsik(2025)Developing a computational model to investigate toxin dynamics in the bioartificial kidney.
Jan Đurović(2025)Investigating the role of ERK signaling in ion channel regulation within the context of Alzheimer’s disease.
Lisa Robben(2025) Correcting metabolic tasks for a Genome-Scale Metabolic Model
Tess Ley (2024) Computational Modelling of P-Cresyl Sulfate Transport via OAT1 in the Human Proximal Tubule
Sakshi Mangala (2024) Computational Modelling of Sorbent-Assisted Peritoneal Dialysis: Modelling Blood Solute Concentrations for Improved Dialysis
Marjolein Ligtvoet (2024) Demographic Analysis of Sorbent-Assisted Peritoneal Dialysis
Andrea Pascaud (2023) Computational modeling of fibrosis
Liv Konrad (2023) Exploring sex differences in toxin transport kinetics in silico
Tien Pham (2023) Modeling sorbent-assisted peritoneal dialysis
Roy Erzurumluoğlu Roy (2023) Determining drug-toxin interaction kinetics via a combined in silico-in vitro approach
Harms M. (2022) Computational modeling of stretch-activated neuronal growth.
Loncol M. (2022) Modeling implant induced fibrosis.
Escarda-Castro E. (2021) Computational model of stretch-activated neuronal signaling.
Donis T. (2020) Computational modeling of isoform-specific PDE influence on cyclic cAMP input
Tomás AR. (2016) Profiling natural and synthetic surface topographies of osteogenic biomaterials
Visiting Researcher
Sakip Önder (2025) work on studying the impact of magnesium on bone healing mechanisms, particularly its role in immunomodulation, using an in silico approach
We work with a lot of wonderful scientists from around the world. We look forward to have a chat if you think we have common interests!